To say I have severe allergies is an understatement. I am so sensitive to dust mites that I not only have to use dust covers; I have to sanitize all of my bedding every week. It is really hard on your comforter and bedspread.
This is the one time I choose to buy cheap. I replaced my comforter and bedspread last year. I did not buy the best quality, but chose modestly priced ones that were marketed for college dorm rooms. I know that the weekly sanitizing will take a toll on them and I do not expect them to last for years.