It was 3 am and I was up, moving allergy screens from the upper windows on one side of the house to the lower windows and doing just the opposite on the other side of the house. I was moving fans and changing their directions also.
I want to avoid using the air conditioner as long as possible. It may be pleasant outside, but hot inside.
I check the direction of the wind 2 or 3 times a day. When it is from the south, I open the lower windows on the south side of the house and the upper windows on the north side of the house. The cool air comes in with the breeze and the warm air goes out the other side of the house. I help the air flow with fans.
Unfortunately, the wind direction changes throughout the day and night. If I happen to wake up in the middle of the night, I check the wind direction. I really want to pull in the cool, night air. Those allergy screens do not let a lot of air through!
My home is slightly angled to the south-east. I do not have any east facing windows. When the wind is coming from the east, I stick a fan in the front door and try to pull it in that way.
I also use curtains to block the heat of the sun, see http://wp.me/pKNzn-jg.
Let the wind cool your house for you.